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Liposomal hydrogel technology
Correa, Grosskopf et al. Matter. 2022.

Publication history prior to Columbia

First and co-first authored publications

  1. Correa S, Meany EL, Gale EC, Klich JH, Saouaf OM, Mayer AT, Xiao Z., Liong CS, Brown RA, Maikawa CL, Grosskopf AK, Mann JL, Idoyaga J, Appel EA, Injectable Nanoparticle-Based Hydrogels Enable the Safe and Effective Deployment of Immunostimulatory CD40 Agonist Antibodies.  Advanced Science. 2022, 2103677. - PDF Download.

  2. Correa S†, Grosskopf AK†, Klich JH, Hernandez HL, Appel EA. Injectable Liposome Based Supramolecular Hydrogels for the Programmable Release of Multiple Protein Drugs. Matter. 2022 Mar 21. doi: 10.1016/j.matt.2022.03.001 - PDF Download.

  3. Correa S, Grosskopf A, Lopez Hernandez H, Chan D, Yu A, Stapleton L, Appel EA. Translational Applications of Hydrogels. Chemical Reviews. 2021; Article ASAP. doi: 10.1021/acs.chemrev.0c01177 - PDF Download.

  4. Correa S, Boehnke N, Barberio AE, Deiss-Yehiely E, Shi A, Oberlton B, Smith SG, Zervantonakis I, Dreaden EC, Hammond PT. Tuning Nanoparticle Interactions with Ovarian Cancer through Layer-by-Layer Modification of Surface Chemistry. ACS Nano. 2020; 14(2):2224-37. doi: 10.1021/acsnano.9b09213 - PDF Download.

  5. Boehnke N†, Correa S†, Hao L†, Wang W, Straehla JP, Bhatia SN, Hammond PT. Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing. Angewandte Chemie. 2020; 59, 2776. doi: 10.1002/anie.201911762 - PDF Download.

  6. Correa S†, Boehnke N†, Deiss-Yehiely E, Hammond PT. Solution Conditions Tune and Optimize Loading of Therapeutic Polyelectrolytes into Layer-by-Layer Functionalized Liposomes. ACS Nano. 2019;13(5):5623-5634. doi: 10.1021/acsnano.9b00792 - PDF Download.

  7. Correa S†, Dreaden EC†, Gu L, Hammond PT. Engineering Nanolayered Particles for Modular Drug Delivery. Journal of Controlled Release. 2016;240:364-386. doi: 10.1016/j.jconrel.2016.01.040 - PDF Download.

  8. Correa S, Choi KY, Dreaden EC, Renggli K, Shi A, Gu L, Shopsowitz KE, Quadir MA, Ben-Akiva E, Hammond PT. Highly Scalable, Closed-Loop Synthesis of Drug-Loaded, Layer-by-Layer Nanoparticles
    Advanced Functional Materials. 2016;26(7):991-1003. doi: 10.1002/adfm.201504385 - PDF Download.

† Indicates co-first authors

Co-authored publications

  1. Grosskopf AK, Labanieh L, Klysz DD, Roth G, Xu P, Adebowale O, Gale EC, Jons CK, Klich JH, Yan J, Maikawa CL, Correa S, Ou B, d’Aquino AI, Cochran JR, Chaudhuri O, Mackall CL, Appel EA. Delivery of CAR-T Cells in a Transient Injectable Stimulatory Hydrogel Niche Improves Treatment of Solid Tumors.
    Science Advances. 2022;8(14):eabn8264.

  2. Seo J-W, Fu K, Correa S, Eisenstein M, Appel EA, Soh HT. Real-time monitoring of drug pharmacokinetics within tumor tissue in live animals. Science Advances. 2022 Jan 7;8(1):eabk2901.

  3. Grosskopf AK, Correa S, Baillet J, Maikawa CL, Gale EC, Brown RA, Appel EA. Consistent Tumorigenesis with Self-Assembled Hydrogels Enables High-powered Murine Cancer Studies. Communications Biology. 2021 Aug 19;4(1):1-7.

  4. Lal RA, Maikawa CL, Lewis D, Baker SW, Smith AA, Roth GA, Gale EC, Stapleton LM, Mann JL, Yu AC, Correa S. Full closed loop open‐source algorithm performance comparison in pigs with diabetes. Clinical and Translational Medicine. 2021 Apr;11(4):e387.

  5. Tošić I, Heppler LN, Egusquiaguirre SP, Boehnke N, Correa S, Costa DF, Moore EA, Pal S, Richardson DS, Ivanov AR, Haas-Kogan DA. Lipidome-based Targeting of STAT3-driven Breast Cancer Cells Using Poly-l-glutamic Acid–coated Layer-by-Layer Nanoparticles Targeting STAT3-driven Breast Cancer with LbL Nanoparticles. Molecular Cancer Therapeutics. 2021 Apr 1;20(4):726-38.

  6. Meis CM, Grosskopf AK, Correa S, Appel EA. Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications. Journal of Visualized Experiments. 2021 Feb 7;168:e62234.

  7. Silva AS, Shopsowitz KE, Correa S, Morton SW, Dreaden EC, Casimiro T, Aguiar-Ricardo A, Hammond PT. Rational Design of Multistage Drug Delivery Vehicles for Pulmonary RNA Interference Therapy. International Journal of Pharmaceutics. 2020 Oct 26:119989.

  8. Smith AA, Gale EC, Roth GA, Maikawa CL, Correa S, Yu AC, Appel EA. Nanoparticles Presenting Potent TLR7/8 Agonists Enhance Anti-PD-L1 Immunotherapy in Cancer Treatment. Biomacromolecules. 2020 Aug 20;21(9):3704-12.

  9. Barberio AE, Smith SG, Correa S, Nguyen C, Nhan B, Melo M, Tokatlian T, Suh H, Irvine DJ, Hammond PT. Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery. ACS Nano. 2020 Jul 21;14(9):11238-53.

  10. Mann JL, Maikawa CL, Smith AA, Grosskopf AK, Baker SW, Roth GA, Meis CM, Gale EC, Liong CS,
    Correa S, Chan D. An Ultrafast Insulin Formulation Enabled by High-Throughput Screening of Engineered Polymeric Excipients. Science Translational Medicine. 2020 Jul 1;12(550).

  11. Maikawa CL, Smith AA, Zou L, Roth GA, Gale EC, Stapleton LM, Baker SW, Mann JL, Anthony CY,
    Correa S, Grosskopf AK. A Co-Formulation of Supramolecularly Stabilized Insulin and Pramlintide Enhances Mealtime Glucagon Suppression in Diabetic Pigs. Nature Biomedical Engineering. 2020 May 11:1-1.

  12. Choi KY, Correa S, Min J, Li J, Roy S, Laccetti KH, Dreaden E, Kong S, Heo R, Roh YH, Lawson EC, Palmer PA, Hammond PT. Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo using Layer-by-Layer Nanoparticles. Advanced Functional Materials. 2019;29(20).

  13. Dreaden EC, Kong YW, Quadir MA, Correa S, Suárez-López L, Barberio AE, Hwang MK, Shi AC, Oberlton B, Gallagher PN, Shopsowitz KE, Elias KM, Yaffe MB, Hammond PT. RNA-Peptide Nanoplexes Drug DNA Damage Pathways in High-Grade Serous Ovarian Tumors. Bioengineering & Translational Medicine. 2018;3(1):26-36.

  14. Dang X, Gu L, Qi J, Correa S, Zhang G, Belcher AM, Hammond PT. Layer-by-Layer Assembled Fluorescent Probes in the Second Near-Infrared Window for Systemic Delivery and Detection of Ovarian Cancer. Proceedings of the National Academy of Sciences. 2016;113(19):5179-84.

  15. Dreaden EC, Kong YW, Morton SW, Correa S, Choi KY, Shopsowitz KE, Renggli K, Drapkin R, Yaffe MB, Hammond PT. Tumor-Targeted Synergistic Blockade of MAPK and PI3K from a Layer-by-Layer Nanoparticle. Clinical Cancer Research. 2015;21(19):4410-9.

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